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Scientific desciption and pharmacological activities of Achillea millefolium

Common Names:
in English: bloodwort, carpenter’s weed, common yarrow, fragrant yarrow, milfoil, nosebleed, sanguinary, sneezeweed, thousand-leaf, thousand-seal, western yarrow, yarrow
in Central America: alhucema, cola de ardilla, hierba del soldado, milen rama, milhojas, plumajillo
in North America: achillee, achillee millefeuille, carpenter’s weed, common yarrow, herbe-a-dinde, milfoil, nosebleed, plumajillo, sanguinary, thousand-leaf, woodchuck tail, woundwort, yarrow
in Brazil: mil-folhas
in South Africa: duisend-blaar-achillea
in China: yang shi cao, shi
in India: accilliya, akarkhara, baranjasif, bhut kesi, biranjasaf, biranjasif, brinjasaf, brinjasif, brinjasuf, buiranjasif, chopandiga, chuang, gandana, gandrain, momadnu, puthkanda, rojmaari, rojmari, rooamari, saigum pharanji, saijum pharangi, tukhm gandana
in Japan: nokogiri-so-zoku
in Pakistan: brinjask

Scientific Names (Synonyms)
Achillea millefolium f. albiflora Dabrowska
Achillea millefolium subsp. alpestris (Wimm. & Grab.) Gremli
Achillea millefolium subsp. alpestris (Wimm. & al.) Murr
Achillea millefolium var. alpestris Wimm. & Grab.
Achillea millefolium var. alpicola (Rydb.) Garrett
Achillea millefolium var. arenicola (A.Heller) Nobs
Achillea millefolium var. arenicola (A.Heller) Ferris
Achillea millefolium var. asplenifolia (Vent.) Farw.
Achillea millefolium subsp. asplenifolia (Vent.) J.Weiss
Achillea millefolium subsp. atrotegula B.Boivin
Achillea millefolium subsp. balearica Sennen
Achillea millefolium subsp. borealis (Bong.) Breitung
Achillea millefolium var. borealis (Bong.) Farw.
Achillea millefolium var. californica (Pollard) Jeps.
Achillea millefolium f. californica (Pollard) H.M.Hall
Achillea millefolium subsp. ceretanica (Sennen) Sennen
Achillea millefolium subsp. collina (Becker ex Rchb.) Weiss
Achillea millefolium subsp. collina (Becker ex Rchb.f.) Oborny
Achillea millefolium var. colliniformis Dabrowska
Achillea millefolium subsp. compacta (Lam.) Bonnier & Layens
Achillea millefolium var. crustata Rochel
Achillea millefolium var. dipetala Dabrowska
Achillea millefolium f. discolor B.Boivin
Achillea millefolium var. dissecta Dabrowska
Achillea millefolium var. fusca (Rydb.) G.N.Jones
Achillea millefolium var. gigantea (Pollard) Ferris
Achillea millefolium var. gigantea (Pollard) Nobs
Achillea millefolium f. iserana (Podp.) Hayek
Achillea millefolium var. iserana Podp.
Achillea millefolium var. lanata W.D.J.Koch
Achillea millefolium var. lanulosa (Nutt.) Piper
Achillea millefolium subsp. lanulosa (Nutt.) Piper
Achillea millefolium var. litoralis Ehrenb. ex Nobs
Achillea millefolium var. lobata Dabrowska
Achillea millefolium var. manshurica Kitam.
Achillea millefolium var. maritima Jeps.
Achillea millefolium var. megacephala (Raup) B.Boivin
Achillea millefolium f. millefolium
Achillea millefolium subsp. millefolium
Achillea millefolium var. millefolium
Achillea millefolium var. nigrescens E.Mey.
Achillea millefolium subsp. occidentalis (DC.) Hyl.
Achillea millefolium var. occidentalis DC.
Achillea millefolium var. pacifica (Rydb.) G.N.Jones
Achillea millefolium subsp. pannonica (Scheele) Hayek
Achillea millefolium subsp. pannonica (Scheele) Oborny
Achillea millefolium var. puberula (Rydb.) Nobs
Achillea millefolium var. puberula (Rydb.) Ferris
Achillea millefolium f. rhodantha Lepage
Achillea millefolium f. rosea (Desf.) E.L.Rand & Redfield
Achillea millefolium var. rosea (Desf.) Torr. & A.Gray
Achillea millefolium f. roseiflora B.Boivin
Achillea millefolium f. roseoides Breitung
Achillea millefolium f. rubicunda (Farw.) Farw.
Achillea millefolium var. rubra Sadler
Achillea millefolium f. scabra (Host) J.Weiss
Achillea millefolium subsp. serpentini Coste & Soulié
Achillea millefolium subsp. setacea (Waldst. & Kit.) Čelak.
Achillea millefolium var. setacea (W.K.) W.D.J.Koch
Achillea millefolium var. sordida W.D.J.Koch
Achillea millefolium var. spathulata Dabrowska
Achillea millefolium subsp. stricta (Schleich. ex Heimerl) Hyl.
Achillea millefolium subsp. sudetica (Opiz) Oborny
Achillea millefolium subsp. sudetica (Opiz) Weiss
Achillea millefolium subsp. tanacetifolia (Fiori) P.Fourn.

Description:
According to Flora of China
  • Herbs, perennial, 40-100 cm tall, with long rhizomes; stems erect, unbranched or branched in upper part, often with short sterile branches at leaf axils above middle, striate, usually white villous.
  • Leaves sessile;
  • leaf blade lanceolate, oblong-lanceolate, or sublinear, 5-20 × 1-2.5 cm, (2 or)3-pinnatisect, abaxially densely villous, adaxially densely depressed glandular punctuate; ultimate segments lanceolate to linear, 0.5-1.5 × 0.3-0.5 mm, apex cartilaginous-mucronulate.
  • Synflorescence a terminal flat-topped panicle 2-6 cm in diam. Capitula many. Involucres oblong or subovoid, ca. 4 × 3 mm;
  • Phyllaries in 3 rows, elliptic or oblong, 1.5-3 × 1-1.3 mm, scarious margin pale yellow or brown; midvein convex. Paleae oblong-elliptic, scarious, abaxially yellow gland-dotted.
  • Ray florets 5; lamina white, pink, or violet-red, suborbicular, 1.5-3 × 2-2.5 mm, apex 2- or 3-denticulate.
  • Disk florets yellow, tubular, 2.2-3 mm, exterior gland-dotted, apex 5-lobed.
  • Achenes greenish, oblong, ca. 2 mm, with white lateral ribs

According to North America
  • Perennials, 6–65+ cm (usually rhizomatous, sometimes stoloniferous).
  • Stems 1(–4), erect, simple or branched, densely lanate-tomentose to glabrate.
  • Leaves petiolate (proximally) or sessile (distally, weakly clasping and gradually reduced); blades oblong or lanceolate, 3.5–35+ cm × 5–35 mm, 1–2-pinnately lobed (ultimate lobes ± lanceolate, often arrayed in multiple planes), faces glabrate to sparsely tomentose or densely lanate.
  • Heads 10–100+, in simple or compound, corymbiform arrays.
  • Phyllaries 20–30 in ± 3 series, (light green, midribs dark green to yellowish, margins green to light or dark brown) ovate to lanceolate, abaxial faces tomentose.
  • Receptacles convex; paleae lanceolate, 1.5–4 mm.
  • Ray florets (3–)5–8, pistillate, fertile; corollas white or light pink to deep purple, laminae 1.5–3 × 1.5–3 mm.
  • Disc florets 10–20; corollas white to grayish white, 2–4.5 mm.
  •  Cypselae 1–2 mm (margins broadly winged)

According to flora of Pakistan
  • Erect, up to 1 m tall, basally woody shrublet with obtuse-angled, punctate-glandulose, woolly pilose twigs. Leaves long-petiolate, green, homomorphic, cauline akin to basal, laxly to densely long soft hairy, linear-lanceolate to oblong, up to 20 x 1 – 4 cm, smaller above, punctate-glandulose, 2–3-pinnatisect, rachis 0.4 – 1.5 mm wide; primary segments numerous, linear to linear-lanceolate;
  • ultimate segments narrowly linear filiform, 0.2 – 0.5 (-1) mm wide, cartilaginous mucronate.
  • Capitula 5 – 6 mm across, up to 150 or sometimes more, on 2 – 5 mm long peduncles, in 5 – 15 cm broad compound corymbs.
  • Involucre oblong to ovoid, 4.5 – 5 x 2.5 – 4 mm, basally rotundate, phyllaries oblong to lanceolate, ± acute to obtuse and laciniate, rarely carinate, pink to brownish scarious on margins.
  • Paleae whitish membranous, with green midrib, lanceolate, obtuse and ± fimbriate, upwards pilose. Ray-florets 4 – 6, with whitish or pale-white, 3-lobed, 1.5 – 2.5 x 1.5 – 3 mm, reflexed limb.
  • Disc-florets 10 – 20, with 2 – 3 mm long, 5-toothed corolla tube.
  • Cypselas oblong, ± flattened, c. 2.5 mm long, glaucous-glabrous, epappose.

Chemicals:
Caffeic acid, Eugenol, (-)-Viburnitol, 3-Methylbutanoic acid, Anacyclin, (-)-Betonicine, Homostachydrine, Trigonelline, Stachydrine, 3-O-Caffeoylquinic acid, p-Cymene, Chamazulene, Achillin, Stigmasterol, Apigenin, Salvigenin, 5-Hydroxy-3,6,7,4'-tetramethoxyflavone, Casticin, Artemetin, Rutin, Millefin, Achillicin, Chamazulene carboxylic acid, proazulene, Galangin, Quercetin, Cosmosiin

Pharmacological activity
Plants suspected of being a photosensitizer; occupational asthma, dermatitis, skin irritation after contact with plant and exposure to sunlight. Fresh herb chewed for toothache. Whole plant antiseptic, anthelmintic,
insecticidal, antibacterial, antimicrobial, antifungal, antiinflammatory, emmenagogue, antispermatogenic, contraceptive, spasmolytic, hepatoprotective, antiperiodic, estrogenic, abortifacient, antiulcer, antioxidant, cytotoxic, used against skin diseases and infections, intestinal worms, hysteria, epilepsy. Leaves used to treat earaches, diarrhea and hemorrhages; powdered leaves given against stomach complaints; infusion used to bathe swellings; leaves for wounds, cuts, bad bruises, to stop bleeding and act as a disinfectant; leaves and stems for spasmodic pains, an infusion taken for colds; leaves as insect repellent.

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